WeĪlso review the different forms of silver present in the environment, and the physio-pharmacology and cutaneous manifestationsĪ 38-year-old Caucasian man presents to our clinic concerned about gray discoloration of the skin. We describe a patient who used oral silver to treat his arthritis, a remedy he was introduced to through the Internet. Their products to unsuspecting consumers using unsubstantiated claims of effectiveness against major illnesses such as AIDS,Ĭancer, arthritis, and infectious diseases. With the proliferation of the Internet, it has become much easier for these manufacturers to market However, recently many health-food manufacturers have promoted colloidal-silver-based With the availability of more effective pharmacologic alternatives, physician-directed use of silver-containing Over the last few decades, there have been several reported problems associated with silver ingestion, including intestinal With an atom of silver it is the most frequently used topical agent for burn treatment. Silver sulfadiazine (1 %) was formulated in 1967 by substituting a portion of the sulfonamide More recently silver arsphenamine has been used in In the pre-antibiotic era, silver was used in nose drops (Argyrol, a silver proteinate), in sinusitis and common-cold remedies,Īnd for the treatment of syphilis (Neo-Silvol, a silver arsphenamine). To wounds to prevent infection in 1897, Crede popularized the use of silver as an anti-infective measure. Halstead of Johns Hopkins University apply silver foil and gauze In the Middle Ages silver nitrate was used for the treatment of nervous system disorders The term argyria was first used by Fuchs in 1840. Text describes a patient with bluish discoloration of the eyes associated with ingestion of silver this mention is probably In 980 AD Avicenna used silver filings as a blood purifier, for offensive breath, and for palpitations of the heart. The first recorded use of silver for medicinal purposes dates back to eighth century. In the metallic form it has been used for making jewelry, silverware, electronic equipment, and dental This released silver is fairly stable it may be taken Wind and rain releases large amounts of silver to the environment. Weathering of silver-bearing rocks and soil by (silver oxide or silver sulfide) that is used in photography and medication. Silver also occurs in the environment as a white powder (silver nitrate and silver chloride), and as a gray-to-black powder Silver is a rare basic element that occurs naturally in our environment as a soft metal. Humans have been exposed to silver and its compounds for centuries via the natural environment, industry, and through the Systemic argyria associated with ingestion of colloidal silverĪkhil Wadhera MD and Max Fung MD Dermatology Online Journal 11 (1): 12 Department of Dermatology, University of California Davis Introduction
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